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Entity Framework Core query error when include subquery

I have this EF query
var r = (from cd in _context.CentoData
.Where(c =>
(string.IsNullOrEmpty(geneName) ? true : c.Gene == geneName) &&
(string.IsNullOrEmpty(codingEffect) ? true : c.CodingEffect == codingEffect) &&
(string.IsNullOrEmpty(zygosity) ? true : c.Zygosity == zygosity) &&
(string.IsNullOrEmpty(sex) ? true : c.Sex == sex) &&
(string.IsNullOrEmpty(clinicalStatement) ? true : c.ClinicalStatement == clinicalStatement) &&
(onsetAge == null ? true : c.AgeAtDiagnosisYearsMonths < onsetAge))
from gs in _context.GnomadSnv
.Where(g => g.Chromosome == cd.Chromosome &&
g.Position == cd.Position &&
g.Ref == cd.RefNt &&
g.Alt == cd.AltNt)
.DefaultIfEmpty()
select new resultType
{
name = cd.name,
AF = g.AF
}
And it works well. But when I when I include a Contains subquery as below (line 9), it pops error saying
"The multi-part identifier "c.Chromosome" could not be bound".
patients is a string list with tens to hundreds elements.
var r = (from cd in _context.CentoData
.Where(c =>
(string.IsNullOrEmpty(geneName) ? true : c.Gene == geneName) &&
(string.IsNullOrEmpty(codingEffect) ? true : c.CodingEffect == codingEffect) &&
(string.IsNullOrEmpty(zygosity) ? true : c.Zygosity == zygosity) &&
(string.IsNullOrEmpty(sex) ? true : c.Sex == sex) &&
(string.IsNullOrEmpty(clinicalStatement) ? true : c.ClinicalStatement == clinicalStatement) &&
(onsetAge == null ? true : c.AgeAtDiagnosisYearsMonths < onsetAge) &&
(patients != null ? patients.Contains(c.RandomPatientId): true))
from gs in _context.GnomadSnv
.Where(g => g.Chromosome == cd.Chromosome &&
g.Position == cd.Position &&
g.Ref == cd.RefNt &&
g.Alt == cd.AltNt)
.DefaultIfEmpty()
select new resultType
{
name = cd.name,
AF = g.AF
}
Did I miss something here?

I want to write LINQ where some condition may be null or not

I want to retrieve some data from database based on some condition, for this I'm using LINQ. But problem is that I don't know how to write LINQ when some condition may be null.
from x in _db.AirWorkOrder
join c in _db.Clients on x.ClientId equals c.Id
where x.CreatedOn >= model.StartDate && x.CreatedOn <= model.EndDate && x.ClientId == model.ClientId && x.Type == model.Type && x.WorkOrderStatus == model.Status
select new DateWisedReportItemModel
I want if the clientID, type, status have null value then it will take all the values saved in the DB. and if there are some values provided in it, then it will work according to the condition.

I presume you're asking how to wildcard things that are null. You need to make the particular clause true if your model value is null. You could do this by saying things like:
(dbcolumn == modelvalue || modelvalue == null) && ...
Or like
(dbcolumn == modelvalue == null ? dbvalue : modelvalue) && ...
Or like
(dbcolumn == modelvalue ?? dbvalue)
For example:
from x in _db.AirWorkOrder
join c in _db.Clients on x.ClientId equals c.Id
where
(x.CreatedOn >= model.StartDate ?? x.CreatedOn) &&
(x.CreatedOn <= model.EndDate == null ? x.CreatedOn : model.EndDate) &&
(x.ClientId == model.ClientId || model.ClientId == null) &&
...
I prefer the first as it is the most easy to understand. Also note carefully that it is the only one that will return the row if the row value in the db is null, because to a database null is never equal to null
I want if there is no condition given in ClientId, type and status then only date(this is mandatory) filter will apply, and if there is condition in these only then these(clientId, type and status) conditions will work
It might be most simple, in terms of code readability to do like:
var baseQuery = from x in _db.AirWorkOrder
join c in _db.Clients on x.ClientId equals c.Id
IEnumerable<...> result;
if(model.ClientId == null && model.Type == null && model.Status == null){
//search on date only
result = baseQuery.Where(x.CreatedOn >= model.StartDate && x.CreatedOn <= model.EndDate);
} else {
//search on no null client/type/status only
result = baseQuery.Where(x =>
(x.ClientId == model.ClientId || model.ClientId == null) &&
(x.Type == model.Type || model.Type == null) &&
(x.WorkOrderStatus == model.Status || model.Status == null);
}

Get parent entity according to some property filter in child table

Id like to get all the parent that doesn't have in the signature table anything with
(Roleid 1 OR Roleid 2 OR Roleid 3) AND SignatureStatus IS <> NULL
RoleId - int: 0-13
SignatureStatus - bit: True, False, Null
I have this code but i still get the parent when i shouldn't and not getting it when i should..
result = Context.APP_AuthorityHasamaForm.Where(x =>
x.UpdateTypeId == (int)UpdateType.Unit && x.AuthorityNum == authorityUnit.AuthorityNum &&
x.InsertDate >= authorityUnit.FromDate && x.HasamaFormStatus == (int)Status.Valid &&
!(x.APP_SignatureAuthorityHasamaForm.Any(s =>
s.RoleId == (int)Role.EligibilityWorker1 || s.RoleId == (int)Role.DepartmentManager2 ||
s.RoleId == (int)Role.Treasurer3 && ((bool)s.SignatureStatus || !(bool)s.SignatureStatus)))).ToList();

How about changing it to be this?
!(x.APP_SignatureAuthorityHasamaForm.Any(s =>
(s.RoleId == (int)Role.EligibilityWorker1 || s.RoleId == (int)Role.DepartmentManager2 ||
s.RoleId == (int)Role.Treasurer3) && s.SignatureStatus.HasValue))).ToList();

I don't have your class structure but here goes few fixes , put brackets outside OR condition and use .HasValue for checking non null :
.Any(s =>
(s.RoleId == (int)Role.EligibilityWorker1 || s.RoleId == (int)Role.DepartmentManager2 ||
s.RoleId == (int)Role.Treasurer3) && ((bool)s.SignatureStatus.hasValue).ToList();

Multiple using of || and && operands

I have a query using Entity Framework. It has many different operands and I am confused with its priority. I am getting the wrong result. I need all records that IsPaid == true or IsPaid == null, also all records must be TypeId == 1 or TypeId == 2, also must be CityId == 1 and CategoryId == 2. For some reason it doesn't evaluate CityId and CategoryId.
What am I doing wrong? Thanks.
var list = db.Ads.Where (x =>
x.IsPaid == true || x.IsPaid == null &&
x.TypeId == 1 || x.TypeId == 2 &&
x.CityId == 1 && x.CategoryId == 2
).ToList();

The best way to solve this problem is using brackets.
You should always use them even if you know the binding prioritys, to increase readability of your code.
(x.IsPaid == true || x.IsPaid == null) && (x.TypeId == 1 || x.TypeId == 2) && x.CityId == 1 && x.CategoryId == 2
&& has a higher proirity than ||
So false && false || true would be translated to (false && false) || true => true
Sidenote as mentioned by #Joey:
Instead of (x.IsPaid == true || x.IsPaid == null) you can write (x.IsPaid != false).

Due to operator precedence, && binds higher than ||.
If you chain Where statements, it's more clear what happens:
var list = db.Ads
.Where(x => x.IsPaid == true || x.IsPaid == null)
.Where(x=> x.TypeId == 1 || x.TypeId == 2)
.Where(x=> x.CityId == 1)
.Where(x=> x.CategoryId == 2)
.ToList();

&& has a higher precedence than ||, just like in math. So, effectively your condition is the following:
x.IsPaid == true ||
x.IsPaid == null && x.TypeId == 1 ||
x.TypeId == 2 && x.CityId == 1 && x.CategoryId == 2
If any of those expressions on separate lines are true, the whole expression is true. You have to use parentheses to clarify here:
(x.IsPaid == true || x.IsPaid == null) &&
(x.TypeId == 1 || x.TypeId == 2) &&
x.CityId == 1 &&
x.CategoryId == 2

Try this:
var list = db.Ads.Where (
(x => x.IsPaid == true || x.IsPaid == null) &&
(x.TypeId == 1 || x.TypeId == 2) &&
(x.CityId == 1 && x.CategoryId == 2)
).ToList();

Why is my query not returning anything

I was writing a LINQ query to filter the records based on user input and selection. Some of the inputs may not be given from the user. So i need to filter based on the given input. I tried giving value for only 1 out of 5 optional inputs. But the query is not returning anything. Please help me to find the proper query. you can better understand after seeing the query.
Code
var model = (from items in Db.Items
where ((items.ItemNo == null ||
items.ItemNo == String.Empty) ||
((items.ItemNo.CompareTo(DD.FromItemNo) >= 0) &&
(items.ItemNo.CompareTo(DD.ToItemNo) <= 0))) &&
(items.InfoTypeId == 0 ||
(items.InfoTypeId == DD.InfoType)) &&
(items.CreatedOn == null ||
(items.CreatedOn >= DD.Start &&
items.CreatedOn <= DD.End)) &&
(items.StatusId == 0 ||
(items.StatusId == DD.Status)) &&
(items.LocationId == 0 ||
(items.LocationId == DD.Location)) &&
(items.CollectionId == 0 ||
(items.CollectionId == DD.Collection))
select new ViewModel()
{
Itemid = items.Id,
INo = items.ItemNo,
BTags = (from asd in Db.BibContents
where asd.BibId == items.BibId &&
asd.TagNo == "245" &&
asd.Sfld == "a"
select asd.Value).FirstOrDefault(),
Sid = (from stat in Db.ItemStatus1
where stat.Id == items.StatusId
select stat.Description).FirstOrDefault(),
Option = DD.Option,
CurrItemNo = DD.ItemNumber
}).ToList();

You've got to check the values of DD for nulls or 0s, not those of items:
var model = (from items in Db.Items
where
(
(DD.ItemNo == null || DD.ItemNo == String.Empty)
|| (items.ItemNo.CompareTo(DD.FromItemNo) >= 0 && items.ItemNo.CompareTo(DD.ToItemNo) <= 0)
)
&& (DD.InfoTypeId == 0 || (items.InfoTypeId == DD.InfoType))
&& (DD.CreatedOn == null || (items.CreatedOn >= DD.Start && items.CreatedOn <= DD.End))
&& (DD.StatusId == 0 || (items.StatusId == DD.Status))
&& (DD.LocationId == 0 || (items.LocationId == DD.Location))
&& (DD.CollectionId == 0 || (items.CollectionId == DD.Collection))
select ...